UniprotKB/SwissProt ID: NUDT4_HUMAN (Q9NZJ9)
Gene Name: NUDT4
Synonyms: DIPP2, KIAA0487
Organism: Homo sapiens (Human).
Function: Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate), PP-InsP4 and [PP]2-InsP4 (bisdiphosphoinositol tetrakisphosphate), suggesting that it may play a role in signal transduction. Also able to catalyze the hydrolysis of dinucleoside oligophosphate Ap6A, but not Ap5A. The major reaction products are ADP and p4a from Ap6A. Also able to hydrolyze 5-phosphoribose 1-diphosphate. Does not play a role in U8 snoRNA decapping activity. Binds U8 snoRNA.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm.
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