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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial

UniprotKB/SwissProt ID: ODBB_MOUSE (Q6P3A8)

Gene Name: Bckdhb

Organism: Mus musculus (Mouse).

Function: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion matrix.

Network with metabolic pathway:
Kegg map ID Pathway Link
map00280"Valine, leucine and isoleucine degradation"
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information

The S-nitrosylation sites of ODBB_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1175YRYRSGDLFN C GSLTIRAPWG   2.84%MC0121278135in vitro
2175YRYRSGDLFN C GSLTIRAPWG   2.84%MC0122865876in vivo
3186GSLTIRAPWG C VGHGALYHSQ   2.68%MC1222865876in vivo
4205SQSPEAFFAH C PGIKVVIPRS   2.71%MC0322865876in vivo
5297SMAQEKLGVS C EVIDLRTIVP   4.50%MC0221278135in vitro
6314TIVPWDVDTV C KSVIKTGRLL   2.70%MC0422865876in vivo
7380EPFYIPDKWK C YDALRKMINY   3.45%MC0221278135in vitro