Protein Name: Oxysterol-binding protein 1
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UniprotKB/SwissProt ID: OSBP1_MOUSE (Q3B7Z2)
Gene Name: Osbp
Synonyms: Kiaa4220
Organism: Mus musculus (Mouse).
Function: Binds cholesterol and a range of oxysterols. Cholesterol binding promotes the formation of a complex with PP2A and a tyrosine phosphatase which dephosphorylate ERK1/2, whereas 25- hydroxycholesterol causes its disassembly. Regulates cholesterol efflux by decreasing ABCA1 stability (By similarity).
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm (By similarity). Golgi apparatus membrane; Peripheral membrane protein (By similarity). Note=When bound to oxysterols, translocates to the periphery of Golgi membranes (By similarity).
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Graphical Visualization of S-nitrosylation Sites:
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| Overview of Protein S-nitrosylation Sites with Functional and Structural Information |  |
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