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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Delta-1-pyrroline-5-carboxylate synthase

UniprotKB/SwissProt ID: P5CS_MOUSE (Q9Z110)

Gene Name: Aldh18a1

Synonyms: P5cs, Pycs

Organism: Mus musculus (Mouse).

Function: Bifunctional enzyme that converts glutamate to glutamate 5-semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion inner membrane.

Network with metabolic pathway:
Kegg map ID Pathway Link
map00330Arginine and proline metabolism
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR000965
IPR001048
IPR001057
IPR005715
IPR005766

The S-nitrosylation sites of P5CS_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1674LRTEYGDLEV C IEVVDSVQEA HHHHHCCCEE E EEEECCHHHH 1.28%MC0820925432in vivo