Protein Name: Astrocytic phosphoprotein PEA-15
|
UniprotKB/SwissProt ID: PEA15_HUMAN (Q15121)
Gene Name: PEA15
Organism: Homo sapiens (Human).
Function: Blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade. Inhibits RPS6KA3 activities by retaining it in the cytoplasm (By similarity). Inhibits both TNFRSF6- and TNFRSF1A-mediated CASP8 activity and apoptosis. Regulates glucose transport by controlling both the content of SLC2A1 glucose transporters on the plasma membrane and the insulin-dependent trafficking of SLC2A4 from the cell interior to the surface.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Note=Associated with microtubules.
| |
|
Graphical Visualization of S-nitrosylation Sites:
|
| Overview of Protein S-nitrosylation Sites with Functional and Structural Information |  |
|
