Protein Name: Peroxisomal biogenesis factor 19
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UniprotKB/SwissProt ID: PEX19_MOUSE (Q8VCI5)
Gene Name: Pex19
Synonyms: Pxf
Organism: Mus musculus (Mouse).
Function: Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3. Excludes CDKN2A from the nucleus and prevents its interaction with MDM2, which results in active degradation of TP53 (By similarity).
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm (By similarity). Peroxisome membrane; Lipid-anchor; Cytoplasmic side (By similarity). Note=Mainly cytoplasmic, some fraction membrane-associated to the outer surface of peroxisomes (By similarity).
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Network with metabolic pathway:
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Graphical Visualization of S-nitrosylation Sites:
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| Overview of Protein S-nitrosylation Sites with Functional and Structural Information |  |
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