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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Plastin-2

UniprotKB/SwissProt ID: PLSL_MOUSE (Q61233)

Gene Name: Lcp1

Synonyms: Pls2

Organism: Mus musculus (Mouse).

Function: Actin-binding protein. Plays a role in the activation of T-cells in response to costimulation through TCR/CD3 and CD2 or CD28. Modulates the cell surface expression of IL2RA/CD25 and CD69 (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytoskeleton. Cell projection (By similarity). Cell junction (By similarity). Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Relocalizes to the immunological synapse between peripheral blood T-lymphocytes

Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR001589
IPR001715
IPR002048
IPR011992

The S-nitrosylation sites of PLSL_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
131VDTDGNGYIS C NELNDLFKAA HCCCCCCEEC H HHHHHHHHHH 3.13%MC1324926564-
231VDTDGNGYIS C NELNDLFKAA HCCCCCCEEC H HHHHHHHHHH 3.13%MC1319483679in vivo
3140INKALENDPD C RHVIPMNPNT HHHHHCCCCC H HHHCCCCCCH 3.84%MC0624926564-
4336REKDDIQRAE C MLQQAERLGC CCCCHHHHHH H HHHHHHHCCC 3.00%MC0524926564-
5336REKDDIQRAE C MLQQAERLGC CCCCHHHHHH H HHHHHHHCCC 3.00%MC0521278135in vitro