UniprotKB/SwissProt ID: PM14_HUMAN (Q9Y3B4)
Gene Name: SF3B14
Organism: Homo sapiens (Human).
Function: Necessary for the splicing of pre-mRNA. Directly contacts the pre-mRNA branch site adenosine for the first catalytic step of splicing. Enters the spliceosome and associates with the pre-mRNA branch site as part of the 17S U2 or, in the case of the minor spliceosome, as part of the 18S U11/U12 snRNP complex, and thus may facilitate the interaction of these snRNP with the branch sites of U2 and U12 respectively.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus (Potential).
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