Protein Name: Serine/threonine-protein phosphatase PP1-gamma catalytic subunit
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UniprotKB/SwissProt ID: PP1G_MOUSE (P63087)
Gene Name: Ppp1cc
Organism: Mus musculus (Mouse).
Function: Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Dephosphorylates RPS6KB1. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density- associated Ca(2+)/calmodulin dependent protein kinase II. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase (By similarity).
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm (By similarity). Nucleus (By similarity). Cleavage furrow (By similarity). Nucleus, nucleolus (By similarity). Nucleus, nucleoplasm (By similarity). Chromosome, centromere, kinetochore (By similarity). Nucleus speckle (By similarity). Midbody (
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Network with metabolic pathway:
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Graphical Visualization of S-nitrosylation Sites:
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Overview of Protein S-nitrosylation Sites with Functional and Structural Information | |
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