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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Thioredoxin-dependent peroxide reductase, mitochondrial

UniprotKB/SwissProt ID: PRDX3_HUMAN (P30048)

Gene Name: PRDX3

Synonyms: AOP1

Organism: Homo sapiens (Human).

Function: Involved in redox regulation of the cell. Protects radical-sensitive enzymes from oxidative damage by a radical- generating system. Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion.

Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR000866
IPR012335
IPR012336

The S-nitrosylation sites of PRDX3_HUMAN

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1229FQYVETHGEV C PANWTPDSPT HHHHHHCCEE C CCCCCCCCCE 1.99%HC0722178444-
2229FQYVETHGEV C PANWTPDSPT HHHHHHCCEE C CCCCCCCCCE 1.99%HC0718335467-
3229FQYVETHGEV C PANWTPDSPT HHHHHHCCEE C CCCCCCCCCE 1.99%HC0719366988-