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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Peroxiredoxin-5, mitochondrial

UniprotKB/SwissProt ID: PRDX5_MOUSE (P99029)

Gene Name: Prdx5

Synonyms: Prdx6

Organism: Mus musculus (Mouse).

Function: Reduces hydrogen peroxide and alkyl hydroperoxides with reducing equivalents provided through the thioredoxin system. Involved in intracellular redox signaling.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion. Cytoplasm. Peroxisome.

Network with metabolic pathway:
Kegg map ID Pathway Link
map04146Peroxisome
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR012335
IPR012336
IPR013740

The S-nitrosylation sites of PRDX5_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
196FGVPGAFTPG C SKTHLPGFVE EEECCCCCCC C CHHHHHHHHH 3.87%MC0622588120-
296FGVPGAFTPG C SKTHLPGFVE EEECCCCCCC C CHHHHHHHHH 3.87%MC0624895380-
396FGVPGAFTPG C SKTHLPGFVE EEECCCCCCC C CHHHHHHHHH 3.87%MC0621278135in vitro
496FGVPGAFTPG C SKTHLPGFVE EEECCCCCCC C CHHHHHHHHH 3.87%MC0622865876in vivo
5200NVEPDGTGLT C SLAPNILSQL EEECCCCCCC H HHHHHHHHHC 3.64%MC1322588120-
6200NVEPDGTGLT C SLAPNILSQL EEECCCCCCC H HHHHHHHHHC 3.64%MC1324895380-
7200NVEPDGTGLT C SLAPNILSQL EEECCCCCCC H HHHHHHHHHC 3.64%MC1321278135in vitro