logo
  Home | Contact us | Browse | Quick Search by UniProtKB ID, Keyword, PDBID

Menu:

Latest news:

Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

Read more...


Protein Name: Presequence protease, mitochondrial

UniprotKB/SwissProt ID: PREP_MOUSE (Q8K411)

Gene Name: Pitrm1

Synonyms: Kiaa1104, Ntup1

Organism: Mus musculus (Mouse).

Function: ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion matrix (By similarity).

Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR001431
IPR007863
IPR011237
IPR011249
IPR013578

The S-nitrosylation sites of PREP_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1556TQQSKHQDAS C LPALKVSDIE HHHCCCCCHH H CCEEEEECCC 5.90%MC0421278135in vitro
2627LFCSVLTKLG C GILNYREQAQ HHHHHHHHCC C CCCCHHHHHH 4.43%MC0221278135in vitro
3780KYLLNCDNMR C SVNATPQQMP HHHHCCCCEE E EEEECCHHHH 3.56%MC1321278135in vitro
4868LPFPVNYIGE C VRTVPYADPD CCCCHHHHHH H CCCCCCCCCC 1.80%MC0622865876in vivo