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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: 26S protease regulatory subunit 6A

UniprotKB/SwissProt ID: PRS6A_HUMAN (P17980)

Gene Name: PSMC3

Synonyms: TBP1

Organism: Homo sapiens (Human).

Function: The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex (By similarity). In case of HIV-1 infection, suppresses Tat-mediated transactivation.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm (Potential). Nucleus (Potential). Cytoplasm, P-body (By similarity). Note=Colocalizes with TRIM5 in the cytoplasmic bodies (By similarity).

Network with metabolic pathway:
Kegg map ID Pathway Link
map03050Proteasome
map05169Epstein-Barr virus infection
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR003593
IPR003959
IPR003960
IPR005937