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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Proteasome subunit beta type-1

UniprotKB/SwissProt ID: PSB1_HUMAN (P20618)

Gene Name: PSMB1

Synonyms: PSC5

Organism: Homo sapiens (Human).

Function: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Nucleus.

PDB :
( If your security settings prevent Jmol from running, please register http://140.138.144.145/ as a safe location in your Java settings. )

Network with metabolic pathway:
Kegg map ID Pathway Link
map03050Proteasome
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR000243
IPR001353

The S-nitrosylation sites of PSB1_HUMAN

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
182YKLTDKTVIG C SGFHGDCLTL EEECCEEEEE E ECCCHHHHHH 2.18%HC1219483679in vivo
289VIGCSGFHGD C LTLTKIIEAR EEEEECCCHH H HHHHHHHHHH 3.56%HC0419483679in vivo
3224DVYTGDALRI C IVTKEGIREE HCCCCCCEEE E EECCCCEEEE 1.33%HC0919483679in vivo