logo
  Home | Contact us | Browse | Quick Search by UniProtKB ID, Keyword, PDBID

Menu:

Latest news:

Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

Read more...


Protein Name: Proteasome subunit beta type-8

UniprotKB/SwissProt ID: PSB8_MOUSE (P28063)

Gene Name: Psmb8

Synonyms: Lmp7, Mc13

Organism: Mus musculus (Mouse).

Function: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides. May be involved in the inflammatory response pathway. Required for adipocyte differentiation.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm (By similarity). Nucleus (By similarity).

PDB :
( If your security settings prevent Jmol from running, please register http://140.138.144.145/ as a safe location in your Java settings. )

Network with metabolic pathway:
Kegg map ID Pathway Link
map03050Proteasome
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR000243
IPR001353

3D Structure Databases:
3D structure databases
EntryMethodResolution (A)ChainPositionsView
3UNF X-ray 2.90 A K/Y73-276Link
3UNH X-ray 3.20 A K/Y73-276Link

The S-nitrosylation sites of PSB8_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1174GMGLSMGSMI C GWDKKGPGLY CCCCEEEEEE E EEECCCCEEE 3.18%MC0421278135in vitro