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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Prostaglandin reductase 2

UniprotKB/SwissProt ID: PTGR2_MOUSE (Q8VDQ1)

Gene Name: Ptgr2

Synonyms: Zadh1

Organism: Mus musculus (Mouse).

Function: Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto- PGE2-alpha with highest activity towards 15-keto-PGE2. Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm (By similarity).

PDB :
( If your security settings prevent Jmol from running, please register http://140.138.144.145/ as a safe location in your Java settings. )

Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information

3D Structure Databases:
3D structure databases
EntryMethodResolution (A)ChainPositionsView
1VJ1 X-ray 2.10 A A1-351Link
2ZB3 X-ray 2.00 A A1-351Link

The S-nitrosylation sites of PTGR2_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1187LLGCSRVVGI C GTQEKCLFLT   3.87%MC0421278135in vitro