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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Trifunctional purine biosynthetic protein adenosine-3

UniprotKB/SwissProt ID: PUR2_HUMAN (P22102)

Gene Name: GART

Synonyms: PGFT, PRGS

Organism: Homo sapiens (Human).

Function:

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

PDB :
( If your security settings prevent Jmol from running, please register http://140.138.144.145/ as a safe location in your Java settings. )

Network with metabolic pathway:
Kegg map ID Pathway Link
map00230Purine metabolism
map00670One carbon pool by folate
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR000115
IPR000728
IPR001555
IPR002376
IPR004607
IPR004733
IPR010918
IPR011054
IPR011761
IPR013815
IPR013816
IPR013817

3D Structure Databases:
3D structure databases
EntryMethodResolution (A)ChainPositionsView
1MEJ X-ray 2.00 A A/B/C810-1010Link
1MEN X-ray 2.23 A A/B/C810-1010Link
1MEO X-ray 1.72 A A808-1010Link
1NJS X-ray 1.98 A A/B808-1010Link
1RBM X-ray 2.30 A A/B808-1010Link
1RBQ X-ray 2.10 A A/B/C/D808-1010Link
1RBY X-ray 2.10 A A/B/C/D808-1010Link
1RBZ X-ray 2.10 A A/B808-1010Link
1RC0 X-ray 2.05 A A/B808-1010Link
1RC1 X-ray 2.25 A A/B808-1010Link
1ZLX X-ray 2.20 A A808-1010Link
1ZLY X-ray 2.07 A A808-1010Link
2QK4 X-ray 2.45 A A/B1-430Link
2V9Y X-ray 2.10 A A/B467-794Link
4EW1 X-ray 1.52 A A810-1010Link
4EW2 X-ray 1.60 A A808-1010Link
4EW3 X-ray 1.70 A A808-1010Link

The S-nitrosylation sites of PUR2_HUMAN

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
141LVAPGNAGTA C SEKISNTAIS EEEECCCHHH H HHHHHHCCCC 5.61%HC0622178444-
293VGNLRSAGVQ C FGPTAEAAQL HHHHHHCCCC E ECCCHHHHHH 3.85%HC122212679in vitro
3298EFNCRFGDPE C QVILPLLKSD EEECCCCCCC C EEEEEECCCC 4.82%HC1219483679in vivo