logo
  Home | Contact us | Browse | Quick Search by UniProtKB ID, Keyword, PDBID

Menu:

Latest news:

Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

Read more...


Protein Name: CAD protein

UniprotKB/SwissProt ID: PYR1_HUMAN (P27708)

Gene Name: CAD

Organism: Homo sapiens (Human).

Function: This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Nucleus. Note=Cytosolic and unphosphorylated in resting cells, translocates to the nucleus in response to EGF stimulation, nuclear import promotes optimal cell growth.

Network with metabolic pathway:
Kegg map ID Pathway Link
map00240Pyrimidine metabolism
map00250"Alanine, aspartate and glutamate metabolism"
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR000991
IPR001317
IPR002082
IPR002195
IPR002474
IPR004722
IPR005479
IPR005480
IPR005481
IPR005483
IPR006130
IPR006131
IPR006132
IPR006220
IPR006274
IPR006275
IPR006680
IPR011059
IPR011607
IPR011702
IPR011761
IPR012998
IPR013816
IPR013817