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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Cytochrome b-c1 complex subunit 6, mitochondrial

UniprotKB/SwissProt ID: QCR6_MOUSE (P99028)

Gene Name: Uqcrh

Organism: Mus musculus (Mouse).

Function: This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1 (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion inner membrane.

Network with metabolic pathway:
Kegg map ID Pathway Link
map00190Oxidative phosphorylation
map04260Cardiac muscle contraction
map05010Alzheimer's disease
map05012Parkinson's disease
map05016Huntington's disease
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information

The S-nitrosylation sites of QCR6_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
135VDPLTTVREH C EQLEKCVKAR   2.82%MC0421278135in vitro
251CVKARERLEL C DNRVSSRSQT   2.96%MC0521278135in vitro
365VSSRSQTEED C TEELFDFLHA   6.12%MC0122588120-
465VSSRSQTEED C TEELFDFLHA   6.12%MC0124895380-
565VSSRSQTEED C TEELFDFLHA   6.12%MC0121278135in vitro
665VSSRSQTEED C TEELFDFLHA   6.12%MC0122865876in vivo