UniprotKB/SwissProt ID: QOR_HUMAN (Q08257)
Gene Name: CRYZ
Organism: Homo sapiens (Human).
Function: Does not have alcohol dehydrogenase activity. Binds NADP and acts through a one-electron transfer process. Orthoquinones, such as 1,2-naphthoquinone or 9,10-phenanthrenequinone, are the best substrates (in vitro). May act in the detoxification of xenobiotics. Interacts with (AU)-rich elements (ARE) in the 3'-UTR of target mRNA species. Enhances the stability of mRNA coding for BCL2. NADPH binding interferes with mRNA binding.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm.
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