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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Ras-related protein Rab-21

UniprotKB/SwissProt ID: RAB21_MOUSE (P35282)

Gene Name: Rab21

Organism: Mus musculus (Mouse).

Function: Regulates integrin internalization and recycling, but does not influence the traffic of endosomally translocated receptors in general. As a result, may regulate cell adhesion and migration. During the mitosis of adherent cells, controls the endosomal trafficking of integrins which is required for the successful completion of cytokinesis.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Endoplasmic reticulum membrane; Lipid- anchor. Golgi apparatus membrane. Early endosome membrane. Cytoplasmic vesicle membrane (By similarity).

Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR001806
IPR003579
IPR005225
IPR013753
IPR015601

The S-nitrosylation sites of RAB21_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
127SFKVVLLGEG C VGKTSLVLRY EEEEEEEECC C CCHHHHHHHH 2.95%MC0321278135in vitro