UniprotKB/SwissProt ID: RB22A_MOUSE (P35285)
Gene Name: Rab22a
Synonyms: Rab22
Organism: Mus musculus (Mouse).
Function: Plays a role in endocytosis and intracellular protein transport. Mediates trafficking of TF from early endosomes to recycling endosomes. Required for NGF-mediated endocytosis of NTRK1, and subsequent neurite outgrowth (By similarity). Binds GTP and GDP and has low GTPase activity. Alternates between a GTP- bound active form and a GDP-bound inactive form.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Endosome membrane; Lipid-anchor (By similarity). Cell membrane; Lipid-anchor (By similarity). Early endosome. Cell projection, ruffle (By similarity). Cytoplasmic vesicle (By similarity). Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic
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