logo
  Home | Contact us | Browse | Quick Search by UniProtKB ID, Keyword, PDBID

Menu:

Latest news:

Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

Read more...


Protein Name: Replication factor C subunit 2

UniprotKB/SwissProt ID: RFC2_HUMAN (P35250)

Gene Name: RFC2

Organism: Homo sapiens (Human).

Function: The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. This subunit binds ATP (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus (Probable).

Network with metabolic pathway:
Kegg map ID Pathway Link
map03420Nucleotide excision repair
map03030DNA replication
map03430Mismatch repair
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR003593
IPR003959
IPR008921
IPR013748

The S-nitrosylation sites of RFC2_HUMAN

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1255FINSENVFKV C DEPHPLLVKE CCCHHHHHHH H HHCCHHHHHH 5.17%HC0919483679in vivo