dbSNO 2.0

Latest news:

Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

Protein Name: 60S ribosomal protein L12

UniprotKB/SwissProt ID: RL12_HUMAN (P30050)

Gene Name: RPL12

Organism: Homo sapiens (Human).

Function: Binds directly to 26S ribosomal RNA (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

Network with metabolic pathway:

Kegg map ID	Pathway	Link
map03010	Ribosome

Graphical Visualization of S-nitrosylation Sites:

Overview of Protein S-nitrosylation Sites with Functional and Structural Information

InterPro ID	Domain
IPR000911

3D Structure Databases:


3D structure databases
Entry	Method	Resolution (A)	Chain	Positions	View
3J3B	EM	5.00 A	K	1-165	Link

The S-nitrosylation sites of RL12_HUMAN

No.	Position	S-nitrosylated Peptide	Secondary Structure of S-nitrosylated Peptide	Solvent Accessibility of nitrosylated Site	Substrate Motifs	PubMed ID	Experiment
1	17	PNEIKVVYLR C TGGEVGATSA	CCEEEEEEEE E ECCCCCCCCC	3.70%	HC02	2212679	in vitro
2	17	PNEIKVVYLR C TGGEVGATSA	CCEEEEEEEE E ECCCCCCCCC	3.70%	HC02	19483679	in vivo
3	141	EILGTAQSVG C NVDGRHPHDI	HHHHHHHHCC E EEECCCHHHH	4.15%	HC12	22178444	-
4	141	EILGTAQSVG C NVDGRHPHDI	HHHHHHHHCC E EEECCCHHHH	4.15%	HC12	2212679	in vitro
5	141	EILGTAQSVG C NVDGRHPHDI	HHHHHHHHCC E EEECCCHHHH	4.15%	HC12	18335467	-
6	141	EILGTAQSVG C NVDGRHPHDI	HHHHHHHHCC E EEECCCHHHH	4.15%	HC12	19366988	-
7	162	IDDINSGAVE C PAS-------	HHHHHCCCEE C CCC	2.47%	HC12	19483679	in vivo

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