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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Adenosylhomocysteinase

UniprotKB/SwissProt ID: SAHH_MOUSE (P50247)

Gene Name: Ahcy

Organism: Mus musculus (Mouse).

Function: Adenosylhomocysteine is a competitive inhibitor of S- adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Melanosome (By similarity).

Network with metabolic pathway:
Kegg map ID Pathway Link
map00270Cysteine and methionine metabolism
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR000043
IPR015878

The S-nitrosylation sites of SAHH_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1195TKSKFDNLYG C RESLIDGIKR HHHHHCCCCC C HHHHHHHHHH 2.49%MC0122178444-
2195TKSKFDNLYG C RESLIDGIKR HHHHHCCCCC C HHHHHHHHHH 2.49%MC0121278135in vitro
3195TKSKFDNLYG C RESLIDGIKR HHHHHCCCCC C HHHHHHHHHH 2.49%MC0120837516in vivo
4228VAGYGDVGKG C AQALRGFGAR EEECCHHHHH H HHHHHHCCCE 2.64%MC0422178444-
5228VAGYGDVGKG C AQALRGFGAR EEECCHHHHH H HHHHHHCCCE 2.64%MC0420837516in vivo