Protein Name: Sodium-dependent noradrenaline transporter
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UniprotKB/SwissProt ID: SC6A2_HUMAN (P23975)
Gene Name: SLC6A2
Synonyms: NAT1, NET1, SLC6A5
Organism: Homo sapiens (Human).
Function: Amine transporter. Terminates the action of noradrenaline by its high affinity sodium-dependent reuptake into presynaptic terminals.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Membrane; Multi-pass membrane protein.
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Protein disease:
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| Disease database |
Database Entry |
Disease information | | KEGG | H01031 | Orthostatic intolerance (OI); Postural tachycardia syndrome (POTS) | | OMIM | 163970 | SOLUTE CARRIER FAMILY 6 (NEUROTRANSMITTER TRANSPORTER, NORADRENALINE), MEMBER 2; SLC6A2 ;;NE | | OMIM | 604715 | ORTHOSTATIC INTOLERANCE ;;NEUROCIRCULATORY ASTHENIA;; MITRAL VALVE PROLAPSE SYNDROME;; IRRIT | | HPRD | 01232 | Orthostatic intolerance |
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Graphical Visualization of S-nitrosylation Sites:
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| Overview of Protein S-nitrosylation Sites with Functional and Structural Information |  |
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