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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Syntenin-1

UniprotKB/SwissProt ID: SDCB1_MOUSE (O08992)

Gene Name: Sdcbp

Organism: Mus musculus (Mouse).

Function: Seems to function as an adapter protein. In adherens junctions may function to couple syndecans to cytoskeletal proteins or signaling components. Seems to couple transcription factor SOX4 to the IL-5 receptor (IL5RA). May also play a role in vesicular trafficking. Seems to be required for the targeting of TGFA to the cell surface in the early secretory pathway.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Membrane; Peripheral membrane protein (By similarity). Melanosome (By similarity).

Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR001478
IPR015590

The S-nitrosylation sites of SDCB1_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1119IKQGIREVIL C KDQDGKIGLR CCCCCEEEEE E ECCCCCEEEE 2.91%MC0220925432in vivo
2240RNGLLTDHHI C EINGQNVIGL HHCCCCCCEE E EECCCCHHCC 3.59%MC0920925432in vivo