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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial

UniprotKB/SwissProt ID: SDHB_HUMAN (P21912)

Gene Name: SDHB

Synonyms: SDH, SDH1

Organism: Homo sapiens (Human).

Function: Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.

Protein disease:
Disease database Database Entry Disease information
HPRD01707Paragangliomas 4
HPRD01707Pheochromocytoma
Network with metabolic pathway:
Kegg map ID Pathway Link
map00020Citrate cycle (TCA cycle)
map00190Oxidative phosphorylation
map05010Alzheimer's disease
map05012Parkinson's disease
map05016Huntington's disease
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information