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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Small glutamine-rich tetratricopeptide repeat-containing protein alpha

UniprotKB/SwissProt ID: SGTA_HUMAN (O43765)

Gene Name: SGTA

Synonyms: SGT, SGT1

Organism: Homo sapiens (Human).

Function: Co-chaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

PDB :
( If your security settings prevent Jmol from running, please register http://140.138.144.145/ as a safe location in your Java settings. )

Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR001440
IPR011990
IPR013026

3D Structure Databases:
3D structure databases
EntryMethodResolution (A)ChainPositionsView
2VYI X-ray 2.40 A A/B84-210Link
4GOD X-ray 1.40 A A/B4-54Link
4GOE X-ray 1.45 A A/B4-54Link
4GOF X-ray 1.35 A A/B4-54Link

The S-nitrosylation sites of SGTA_HUMAN

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1129ELNPANAVYF C NRAAAYSKLG HHCCCCHHHH H HHHHHHHHHC 1.52%HC0519483679in vivo
2148LGNYAGAVQD C ERAICIDPAY HCCHHHHHHH H HHHHHHCCCC 1.82%HC052212679in vitro
3148LGNYAGAVQD C ERAICIDPAY HCCHHHHHHH H HHHHHHCCCC 1.82%HC0519483679in vivo
4153GAVQDCERAI C IDPAYSKAYG HHHHHHHHHH H HCCCCHHHHH 2.55%HC0419483679in vivo