Protein Name: SRA stem-loop-interacting RNA-binding protein, mitochondrial
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UniprotKB/SwissProt ID: SLIRP_HUMAN (Q9GZT3)
Gene Name: SLIRP
Synonyms: C14orf156
Organism: Homo sapiens (Human).
Function: RNA-binding protein that acts as a nuclear receptor corepressor. Probably acts by binding the SRA RNA, and repressing the SRA-mediated nuclear receptor coactivation. Binds the STR7 loop of SRA RNA. Also able to repress glucocorticoid (GR), androgen (AR), thyroid (TR) and VDR-mediated transactivation.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion. Nucleus. Note=Predominantly mitochondrial. Some fraction is nuclear. In the nucleus, it is recruited to nuclear receptor target promoters.
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Graphical Visualization of S-nitrosylation Sites:
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| Overview of Protein S-nitrosylation Sites with Functional and Structural Information |  |
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