logo
  Home | Contact us | Browse | Quick Search by UniProtKB ID, Keyword, PDBID

Menu:

Latest news:

Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

Read more...


Protein Name: Staphylococcal nuclease domain-containing protein 1

UniprotKB/SwissProt ID: SND1_HUMAN (Q7KZF4)

Gene Name: SND1

Synonyms: TDRD11

Organism: Homo sapiens (Human).

Function: Functions as a bridging factor between STAT6 and the basal transcription factor. Plays a role in PIM1 regulation of MYB activity. Functions as a transcriptional coactivator for the Epstein-Barr virus nuclear antigen 2 (EBNA2).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Nucleus. Melanosome. Note=In IL-4 stimulated cells colocalizes with STAT6 in the nucleus. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

PDB :
( If your security settings prevent Jmol from running, please register http://140.138.144.145/ as a safe location in your Java settings. )

Network with metabolic pathway:
Kegg map ID Pathway Link
map05169Epstein-Barr virus infection
map05203Viral carcinogenesis
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR002071
IPR002999
IPR006021
IPR006022
IPR008191
IPR008192

3D Structure Databases:
3D structure databases
EntryMethodResolution (A)ChainPositionsView
2E6N NMR - A704-800Link
2HQE X-ray 2.00 A A/B665-910Link
2HQX X-ray 1.42 A A/B665-910Link
2O4X X-ray 2.00 A A679-895Link
B705-795
3BDL X-ray 1.90 A A340-888Link
3OMC X-ray 1.77 A A/B650-910Link
3OMG X-ray 1.85 A A/B650-910Link

The S-nitrosylation sites of SND1_HUMAN

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1440ETVPAFSERT C ATVTIGGINI HCCCCCCCCC E EEEEECCCHH 3.61%HC0319483679in vivo