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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Synaptosomal-associated protein 23

UniprotKB/SwissProt ID: SNP23_HUMAN (O00161)

Gene Name: SNAP23

Organism: Homo sapiens (Human).

Function: Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cell membrane; Peripheral membrane protein. Cell membrane; Lipid-anchor. Cell junction, synapse, synaptosome. Note=Mainly localized to the plasma membrane.

PDB :
( If your security settings prevent Jmol from running, please register http://140.138.144.145/ as a safe location in your Java settings. )

Protein disease:
Disease database Database Entry Disease information
OMIM602534SYNAPTOSOMAL-ASSOCIATED PROTEIN, 23-KD; SNAP23 ;;SNAP23A SNAP23B;; SNAP23C;; SNAP23D;; SNAP2
Network with metabolic pathway:
Kegg map ID Pathway Link
map04130SNARE interactions in vesicular transport
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR000727
IPR000928

The S-nitrosylation sites of SNP23_HUMAN

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1112TWGDGGENSP C NVVSKQPGPV CCCCCCCCCH H HHHHCCCHHH 6.40%HC122212679
(Cys69)
in vitro