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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Sorting nexin-4

UniprotKB/SwissProt ID: SNX4_HUMAN (O95219)

Gene Name: SNX4

Organism: Homo sapiens (Human).

Function: May be involved in several stages of intracellular trafficking. Plays a role in recycling endocytosed transferrin receptor and prevent its degradation.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Note=Also detected on a juxtanuclear endocytic recycling compartment (ERC).

Protein disease:
Disease database Database Entry Disease information
OMIM605931SORTING NEXIN 4; SNX4
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR001683

The S-nitrosylation sites of SNX4_HUMAN

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1172LLRIASHPIL C RDKIFYLFLT HHHHHCCCCC C CCHHHHHHCC 5.68%HC0619483679in vivo