dbSNO 2.0

Latest news:

Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

Protein Name: Spartin

UniprotKB/SwissProt ID: SPG20_HUMAN (Q8N0X7)

Gene Name: SPG20

Synonyms: KIAA0610, TAHCCP1

Organism: Homo sapiens (Human).

Function: May be implicated in endosomal trafficking, or microtubule dynamics, or both.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Note=Transiently associated with endosomes.

PDB :
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Protein disease:

Disease database	Database Entry	Disease information
HPRD	06170	Spastic paraplegia 20, autosomal recessive

Graphical Visualization of S-nitrosylation Sites:

Overview of Protein S-nitrosylation Sites with Functional and Structural Information

InterPro ID	Domain
IPR007330

3D Structure Databases:


3D structure databases
Entry	Method	Resolution (A)	Chain	Positions	View
2DL1	NMR	-	A	9-111	Link

The S-nitrosylation sites of SPG20_HUMAN

No.	Position	S-nitrosylated Peptide	Secondary Structure of S-nitrosylated Peptide	Solvent Accessibility of nitrosylated Site	Substrate Motifs	PubMed ID	Experiment
1	499	KVSQFLVDGV C TVANCVGKEL	HHHHHHHHHH H HHHHHHHHHH	2.87%	HC12	19483679	in vivo
2	504	LVDGVCTVAN C VGKELAPHVK	HHHHHHHHHH H HHHHHHHHHH	2.85%	HC06	19483679	in vivo

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