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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Spectrin beta chain, non-erythrocytic 1

UniprotKB/SwissProt ID: SPTB2_MOUSE (Q62261)

Gene Name: Sptbn1

Synonyms: Elf, Spnb-2, Spnb2, Sptb2

Organism: Mus musculus (Mouse).

Function: Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytoskeleton. Cytoplasm, myofibril, sarcomere, M line. Note=Colocalizes with ANK2 in a distinct intracellular compartment of neonatal cardiomyocytes. Isoform 2: Cell membrane; Peripheral membrane protein; Cytoplasmic side.

PDB :
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Network with metabolic pathway:
Kegg map ID Pathway Link
map04530Tight junction
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR001589
IPR001605
IPR001715
IPR001849
IPR002017
IPR011993

3D Structure Databases:
3D structure databases
EntryMethodResolution (A)ChainPositionsView
1BTN X-ray 2.00 A A2199-2304Link
1MPH NMR - A2199-2304Link

The S-nitrosylation sites of SPTB2_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
11389ANKAELFTQS C ADLDKWLHGL HHHHHHHHHH H HHHHHHHHHH 2.16%MC0420925432in vivo