UniprotKB/SwissProt ID: SUCD_ECOLI (P0AGE9)
Gene Name: sucD
Organism: Escherichia coli (strain K12).
Function: During aerobic metabolism it functions in the citric acid cycle, coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents an important site of substrate-level phosphorylation. It can also function in the other direction for anabolic purposes, and this may be particularly important for providing succinyl-CoA during anaerobic growth when the oxidative route from 2-oxoglutarate is severely repressed. The alpha-subunit binds CoA, as well as ATP and catalyzes phosphoryl transfer to one of its histidine residues. The complete active site is probably located in the region of alpha-beta contact.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization:
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PDB :
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