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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Alanine--tRNA ligase, cytoplasmic

UniprotKB/SwissProt ID: SYAC_MOUSE (Q8BGQ7)

Gene Name: Aars

Organism: Mus musculus (Mouse).

Function: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm (By similarity).

Network with metabolic pathway:
Kegg map ID Pathway Link
map00970Aminoacyl-tRNA biosynthesis
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR002318
IPR003156
IPR012947

The S-nitrosylation sites of SYAC_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1903DNEAGKITCL C QVPQNAANRG ECCCCEEEEE E ECCHHHHHCC 4.11%MC0320925432in vivo