Protein Name: Glycine--tRNA ligase
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UniprotKB/SwissProt ID: SYG_HUMAN (P41250)
Gene Name: GARS
Organism: Homo sapiens (Human).
Function: Catalyzes the attachment of glycine to tRNA(Gly). Is also able produce diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Mitochondrion.
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Protein disease:
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Disease database |
Database Entry |
Disease information | HPRD | 02617 | Charcot-Marie-tooth disease, axonal, type 2D | HPRD | 02617 | Neuronopathy, distal hereditary motor, type V |
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Network with metabolic pathway:
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Graphical Visualization of S-nitrosylation Sites:
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Overview of Protein S-nitrosylation Sites with Functional and Structural Information | |
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