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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Glycine--tRNA ligase

UniprotKB/SwissProt ID: SYG_MOUSE (Q9CZD3)

Gene Name: Gars

Organism: Mus musculus (Mouse).

Function: Catalyzes the attachment of glycine to tRNA(Gly). Is also able produce diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm (By similarity). Mitochondrion (By similarity).

Network with metabolic pathway:
Kegg map ID Pathway Link
map00970Aminoacyl-tRNA biosynthesis
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR000738
IPR002314
IPR002315
IPR004154
IPR006195

The S-nitrosylation sites of SYG_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1451TSYGWIEIVG C ADRSCYDLSC CCCCCEEEEE E EECCCCCHHH 2.17%MC1222865876in vivo