logo
  Home | Contact us | Browse | Quick Search by UniProtKB ID, Keyword, PDBID

Menu:

Latest news:

Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

Read more...


Protein Name: Arginine--tRNA ligase, cytoplasmic

UniprotKB/SwissProt ID: SYRC_HUMAN (P54136)

Gene Name: RARS

Organism: Homo sapiens (Human).

Function: Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis. Modulates the secretion of AIMP1 and may be involved in generation of the inflammatory cytokine EMAP2 from AIMP1.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm.

Network with metabolic pathway:
Kegg map ID Pathway Link
map00970Aminoacyl-tRNA biosynthesis
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR001278
IPR001412
IPR005148
IPR008909
IPR009080
IPR014729
IPR015945

The S-nitrosylation sites of SYRC_HUMAN

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1369DGRKIVFVPG C SIPLTIVKSD CCEEEEECCC C CCCCEEEECC 2.46%HC0119483679in vivo