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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Tubulin alpha-1A chain

UniprotKB/SwissProt ID: TBA1A_RAT (P68370)

Gene Name: Tuba1a

Synonyms: Tuba1

Organism: Rattus norvegicus (Rat).

Function: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytoskeleton.

Network with metabolic pathway:
Kegg map ID Pathway Link
map04540Gap junction
map04145Phagosome
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR000217
IPR002452
IPR003008
IPR008280

The S-nitrosylation sites of TBA1A_RAT

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1295QLSVAEITNA C FEPANQMVKC CCCHHHHHHH H HCCCCCEEEC 4.27%RC0422178444-
2295QLSVAEITNA C FEPANQMVKC CCCHHHHHHH H HCCCCCEEEC 4.27%RC0416418269in vitro
3315CDPRHGKYMA C CLLYRGDVVP CCCCCCHHHH H HHHHCCCCCH 0.67%RC0422178444-
4315CDPRHGKYMA C CLLYRGDVVP CCCCCCHHHH H HHHHCCCCCH 0.67%RC0417629318in vitro
5316DPRHGKYMAC C LLYRGDVVPK CCCCCHHHHH H HHHCCCCCHH 1.81%RC0422178444-
6316DPRHGKYMAC C LLYRGDVVPK CCCCCHHHHH H HHHCCCCCHH 1.81%RC0417629318in vitro
7347TKRTIQFVDW C PTGFKVGINY HHHCCCCCCC C CCCEECCCCC 1.55%RC0122178444-
8347TKRTIQFVDW C PTGFKVGINY HHHCCCCCCC C CCCEECCCCC 1.55%RC0117629318in vitro
9376GDLAKVQRAV C MLSNTTAIAE CCHHHHHHHH H HHHHHHHHHH 1.90%RC0422178444-
10376GDLAKVQRAV C MLSNTTAIAE CCHHHHHHHH H HHHHHHHHHH 1.90%RC0417629318in vitro