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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Tubulin alpha-1B chain

UniprotKB/SwissProt ID: TBA1B_HUMAN (P68363)

Gene Name: TUBA1B

Organism: Homo sapiens (Human).

Function: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytoskeleton.

PDB :
( If your security settings prevent Jmol from running, please register http://140.138.144.145/ as a safe location in your Java settings. )

Network with metabolic pathway:
Kegg map ID Pathway Link
map05130Pathogenic Escherichia coli infection
map04540Gap junction
map04145Phagosome
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR000217
IPR002452
IPR003008
IPR008280

The S-nitrosylation sites of TBA1B_HUMAN

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1295QLSVAEITNA C FEPANQMVKC CCCHHHHHHH H HCCCCCEEEC 4.27%HC0825040305in vivo
2316DPRHGKYMAC C LLYRGDVVPK CCCCCHHHHH H HHHCCCCCHH 1.81%HC1125040305in vivo
3347TKRSIQFVDW C PTGFKVGINY HHHCCCCCCC C CCCEECCCCC 1.55%HC0725040305in vivo
4376GDLAKVQRAV C MLSNTTAIAE CCHHHHHHHH H HHHHHHHHHH 1.90%HC0425040305in vivo