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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Tubulin beta-5 chain

UniprotKB/SwissProt ID: TBB5_MOUSE (P99024)

Gene Name: Tubb5

Organism: Mus musculus (Mouse).

Function: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytoskeleton.

Network with metabolic pathway:
Kegg map ID Pathway Link
map04540Gap junction
map04145Phagosome
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR000158
IPR000217
IPR002453
IPR003008
IPR008280
IPR013838

The S-nitrosylation sites of TBB5_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
112REIVHIQAGQ C GNQIGAKFWE CEEEEEECCH H HHHHHHHHHH 5.60%MC0522588120-
212REIVHIQAGQ C GNQIGAKFWE CEEEEEECCH H HHHHHHHHHH 5.60%MC0524926564-
312REIVHIQAGQ C GNQIGAKFWE CEEEEEECCH H HHHHHHHHHH 5.60%MC0520925432in vivo
4239VSATMSGVTT C LRFPGQLNAD HHHHHHHHHC C CCCCCEEECC 1.55%MC0620925432in vivo
5303VFDAKNMMAA C DPRHGRYLTV HHHHCCCEEE C CCCCCHHHHH 5.55%MC0224926564-
6354WIPNNVKTAV C DIPPRGLKMA CCCCCEEEEC C CCCCCCCCEE 3.49%MC0422588120-
7354WIPNNVKTAV C DIPPRGLKMA CCCCCEEEEC C CCCCCCCCEE 3.49%MC0424926564-