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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Tubulin-folding cofactor B

UniprotKB/SwissProt ID: TBCB_MOUSE (Q9D1E6)

Gene Name: Tbcb

Synonyms: Ckap1

Organism: Mus musculus (Mouse).

Function: Binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer (By similarity). Involved in regulation of tubulin heterodimer dissociation. May function as a negative regulator of axonal growth.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Cytoplasm, cytoskeleton. Note=Colocalizes with microtubules. In differentiated neurons, located in the cytoplasm. In differentiating neurons, accumulates at the growth cone.

PDB :
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Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR000938

3D Structure Databases:
3D structure databases
EntryMethodResolution (A)ChainPositionsView
1V6E NMR - A11-92Link
1WHG NMR - A134-233Link

The S-nitrosylation sites of TBCB_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
183LLGSYPVDDG C RIHVIDHSGV HHCCCCCCCC C EEEEEECCCC 4.80%MC0521278135in vitro