dbSNO 2.0

Latest news:

Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

Protein Name: TBC1 domain family member 4

UniprotKB/SwissProt ID: TBCD4_MOUSE (Q8BYJ6)

Gene Name: Tbc1d4

Synonyms: As160, Kiaa0603

Organism: Mus musculus (Mouse).

Function: May act as a GTPase-activating protein for RAB2A, RAB8A, RAB10 and RAB14. Promotes insulin-induced glucose transporter SLC2A4/GLUT4 translocation at the plasma membrane, thus increasing glucose uptake (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Note=Cytoplasmic perinuclear (By similarity).

Graphical Visualization of S-nitrosylation Sites:

Overview of Protein S-nitrosylation Sites with Functional and Structural Information

InterPro ID	Domain
IPR000195
IPR006020
IPR011993

The S-nitrosylation sites of TBCD4_MOUSE

No.	Position	S-nitrosylated Peptide	Secondary Structure of S-nitrosylated Peptide	Solvent Accessibility of nitrosylated Site	Substrate Motifs	PubMed ID	Experiment
1	74	RRSQKPDAGG C GAPAAREVIL	HHHCCCCCCC C CCCCCCEEEE	4.04%	MC02	22865876	in vivo

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