UniprotKB/SwissProt ID: TCEA1_HUMAN (P23193)
Gene Name: TCEA1
Synonyms: GTF2S, TFIIS
Organism: Homo sapiens (Human).
Function: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus.
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