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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: T-complex protein 1 subunit epsilon

UniprotKB/SwissProt ID: TCPE_MOUSE (P80316)

Gene Name: Cct5

Synonyms: Ccte, Kiaa0098

Organism: Mus musculus (Mouse).

Function: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm (By similarity). Cytoplasm, cytoskeleton, microtubule organizing center, centrosome (By similarity).

Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR001844
IPR002194
IPR002423
IPR008950
IPR012718

The S-nitrosylation sites of TCPE_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1181TTLGSKVINS C HRQMAEIAVN HHCCHHHHHH H HHHHHHHHHH 2.37%MC0620925432in vivo
2253VVDAKIAILT C PFEPPKPKTK CCCCEEEEEE C CCCCCCCCCC 3.05%MC0220925432in vivo
3253VVDAKIAILT C PFEPPKPKTK CCCCEEEEEE C CCCCCCCCCC 3.05%MC0221278135in vitro
4407EAKRSLHDAL C VIRNLIRDNR HHHHHHHHHH H HHHHHHHCCC 2.28%MC0124926564-
5407EAKRSLHDAL C VIRNLIRDNR HHHHHHHHHH H HHHHHHHCCC 2.28%MC0120925432in vivo
6407EAKRSLHDAL C VIRNLIRDNR HHHHHHHHHH H HHHHHHHCCC 2.28%MC0121278135in vitro
7493KESNPALGID C LHKGSNDMQY HCCCCCEEEE C CCCCCHHHHH 3.97%MC0620925432in vivo