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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: T-complex protein 1 subunit theta

UniprotKB/SwissProt ID: TCPQ_MOUSE (P42932)

Gene Name: Cct8

Synonyms: Cctq

Organism: Mus musculus (Mouse).

Function: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm (By similarity). Cytoplasm, cytoskeleton, microtubule organizing center, centrosome (By similarity).

Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR002194
IPR002423
IPR008950
IPR012721

The S-nitrosylation sites of TCPQ_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1148KAHEILPELV C CSAKNLRDVD HHHHHHHHHH H CCCCCCCCHH 2.07%MC0520925432in vivo
2244VKDAKIAVYS C PFDGMITETK ECCCEEEEEE C CCCCCHHHCC 1.82%MC0824926564-
3430AKQITSYGET C PGLEQYAIKK HHHHHHHHHC C CHHHHHHHHH 1.88%MC0324926564-