UniprotKB/SwissProt ID: TOP2A_HUMAN (P11388)
Gene Name: TOP2A
Synonyms: TOP2
Organism: Homo sapiens (Human).
Function: Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Nucleus, nucleoplasm. Note=Generally located in the nucleoplasm.
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