UniprotKB/SwissProt ID: TPA_HUMAN (P00750)
Gene Name: PLAT
Organism: Homo sapiens (Human).
Function: Converts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminogen. By controlling plasmin-mediated proteolysis, it plays an important role in tissue remodeling and degradation, in cell migration and many other physiopathological events. Plays a direct role in facilitating neuronal migration.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Secreted, extracellular space.
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